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Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water-Soluble Pillar[6]arene
[Image: see text] Water-soluble pillar[6]arene (WP6) was used to solubilize camptothecin family antitumor drugs. In the presence of WP6, the solubility of camptothecin (CPT) and 10-hydroxycamptothecin (HCPT) was enhanced by 380 and 40 times, respectively. The solubility enhancement is proved to be t...
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| Publicado en: | ACS Omega |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2017
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044948/ https://ncbi.nlm.nih.gov/pubmed/30023745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01032 |
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