TMPyP Inhibits Amyloid-β Aggregation and Alleviates Amyloid-Induced Cytotoxicity

[Image: see text] The aggregation or misfolding of amyloid-β (Aβ) is a major pathological hallmark of Alzheimer’s disease (AD). The regulation of Aβ aggregation is thought to be an effective strategy for AD treatment. The capability of a water-soluble porphyrin, 5,10,15,20-tetrakis(N-methyl-4-pyridy...

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Publicado en:ACS Omega
Autores principales: Fan, Yujuan, Wu, Daohong, Yi, Xinyao, Tang, Hailin, Wu, Ling, Xia, Yonghong, Wang, Zixiao, Liu, Qiuhua, Zhou, Zaichun, Wang, Jianxiu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2017
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044923/
https://ncbi.nlm.nih.gov/pubmed/30023716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00877
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