Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs

[Image: see text] We describe the design and optimization of polyfunctional scaffolds based on a fluorescent indolizine core derivatized with various orthogonal groups (amines, esters, oximes, alkynes, etc.). To show one application as tools in biology, the scaffold was used to prepare drug–biotin c...

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Bibliografske podrobnosti
izdano v:ACS Omega
Main Authors: Arvin-Berod, Marie, Desroches-Castan, Agnès, Bonte, Simon, Brugière, Sabine, Couté, Yohann, Guyon, Laurent, Feige, Jean-Jacques, Baussanne, Isabelle, Demeunynck, Martine
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2017
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044919/
https://ncbi.nlm.nih.gov/pubmed/30023604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01184
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