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Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs
[Image: see text] We describe the design and optimization of polyfunctional scaffolds based on a fluorescent indolizine core derivatized with various orthogonal groups (amines, esters, oximes, alkynes, etc.). To show one application as tools in biology, the scaffold was used to prepare drug–biotin c...
Enregistré dans:
| Publié dans: | ACS Omega |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2017
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044919/ https://ncbi.nlm.nih.gov/pubmed/30023604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01184 |
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