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Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs

[Image: see text] We describe the design and optimization of polyfunctional scaffolds based on a fluorescent indolizine core derivatized with various orthogonal groups (amines, esters, oximes, alkynes, etc.). To show one application as tools in biology, the scaffold was used to prepare drug–biotin c...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:ACS Omega
Päätekijät: Arvin-Berod, Marie, Desroches-Castan, Agnès, Bonte, Simon, Brugière, Sabine, Couté, Yohann, Guyon, Laurent, Feige, Jean-Jacques, Baussanne, Isabelle, Demeunynck, Martine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2017
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044919/
https://ncbi.nlm.nih.gov/pubmed/30023604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01184
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