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Naphthalenediimide-Linked Bisbenzimidazole Derivatives as Telomeric G-Quadruplex-Stabilizing Ligands with Improved Anticancer Activity
[Image: see text] Human telomeric G-quadruplex DNA stabilization has emerged as an exciting novel approach for anticancer drug development. In the present study, we have designed and synthesized three C(2)-symmetric bisubstituted bisbenzimidazole naphthalenediimide (NDI) ligands, ALI-C(3), BBZ-ARO,...
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| Izdano u: | ACS Omega |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2017
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| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044781/ https://ncbi.nlm.nih.gov/pubmed/30023623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00523 |
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