Design, Synthesis and Evaluation of Bifunctional Acridinine−Naphthalenediimide Redox-Active Conjugates as Antimalarials

[Image: see text] A novel class of bifunctional molecules was synthesized integrating acridine (Ac) and redox-active naphthalenediimide (NDI) scaffolds directly and through a flexible linker (en). We evaluated in vitro antiplasmodial activity, physicochemical properties, and a possible mode of actio...

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Détails bibliographiques
Publié dans:ACS Omega
Auteurs principaux: Dana, Srikanta, Keshri, Sudhir Kumar, Shukla, Jyoti, Vikramdeo, Kunwar Somesh, Mondal, Neelima, Mukhopadhyay, Pritam, Dhar, Suman Kumar
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2016
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044610/
https://ncbi.nlm.nih.gov/pubmed/30023479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.6b00060
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