Effect of green tea catechins on the pharmacokinetics of digoxin in humans

BACKGROUND: Previous in vitro studies have reported the inhibitory effect of green tea on p-glycoprotein (p-gp) encoded by ABCB1. This study aimed to investigate the effect of green tea on the pharmacokinetics of digoxin, a typical probe drug of p-gp. METHODS: Sixteen healthy volunteers participated...

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Publicat a:Drug Des Devel Ther
Autors principals: Kim, Tae-Eun, Shin, Kwang-Hee, Park, Jeong-Eun, Kim, Min-Gul, Yun, Yeo-Min, Choi, Dong-Hee, Kwon, Kyoung Ja, Lee, Jongmin
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044363/
https://ncbi.nlm.nih.gov/pubmed/30022812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S148257
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