Systemic lidocaine inhibits high-mobility group box 1 messenger ribonucleic acid expression and protein in BALB/c mice after closed fracture musculoskeletal injury

BACKGROUND: Severe musculoskeletal trauma can trigger an inflammatory response, and an excessive inflammatory response can lead to systemic inflammatory response syndrome and multiorgan failure. High-mobility group box 1 (HMGB1) is an early mediator pro-inflammatory cytokine in sterile injuries and...

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Dades bibliogràfiques
Publicat a:Saudi J Anaesth
Autors principals: Sirait, Robert Hotman, Hatta, Mochammad, Ramli, Muhammad, Islam, Andi Asadul, Arief, Syafrie Kamsul
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044174/
https://ncbi.nlm.nih.gov/pubmed/30100837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/sja.SJA_685_17
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