Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

Chemotherapy-induced hemorrhagic cystitis (CHC) can be difficult to manage. Prior work suggests that IL-4 alleviates ifosfamide-induced hemorrhagic cystitis (IHC), but systemically administered IL-4 causes significant side effects. We hypothesized that the Schistosoma hematobium homolog of IL-4-indu...

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Publicat a:FASEB J
Autors principals: Mbanefo, Evaristus C., Le, Loc, Pennington, Luke F., Odegaard, Justin I., Jardetzky, Theodore S., Alouffi, Abdulaziz, Falcone, Franco H., Hsieh, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044057/
https://ncbi.nlm.nih.gov/pubmed/29613835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701415R
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