Isolation of T cell receptors targeting recurrent neoantigens in hematological malignancies

Mutation-derived neoantigens represent an important class of tumour-specific, tumour rejection antigens, and are attractive targets for TCR gene therapy of cancer. The majority of such mutations are patient-specific and targeting these requires a fully personalized approach. However, some mutations...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Tubb, Vanessa M., Schrikkema, Deborah S., Croft, Nathan P., Purcell, Anthony W., Linnemann, Carsten, Freriks, Manon R., Chen, Frederick, Long, Heather M., Lee, Steven P., Bendle, Gavin M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044029/
https://ncbi.nlm.nih.gov/pubmed/30001747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0386-y
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