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Modelling population-level impact to inform target product profiles for childhood malaria vaccines

BACKGROUND: The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5–17-month-old children in phase 3 trials, and from 2018, the vaccine will be evaluated through a large-scale pilot implementation program. Work is ongoing to optimise this vaccine, with higher eff...

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Pubblicato in:BMC Med
Autori principali: Hogan, Alexandra B., Winskill, Peter, Verity, Robert, Griffin, Jamie T., Ghani, Azra C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044028/
https://ncbi.nlm.nih.gov/pubmed/30001708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1095-6
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