Differentially methylated loci in NAFLD cirrhosis are associated with key signaling pathways

Altered DNA methylation events contribute to the pathogenesis and progression of metabolic disorders, including nonalcoholic fatty liver disease (NAFLD). Investigations of global DNA methylation patterns in liver biopsies representing severe NAFLD fibrosis have been limited. We used the HumanMethyla...

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Bibliographic Details
Published in:Clin Epigenetics
Main Authors: Gerhard, Glenn S., Malenica, Ivana, Llaci, Lorida, Chu, Xin, Petrick, Anthony T., Still, Christopher D., DiStefano, Johanna K.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044005/
https://ncbi.nlm.nih.gov/pubmed/30005700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0525-9
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