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Angelica gigas Nakai and Decursin Downregulate Myc Expression to Promote Cell Death in B-cell Lymphoma

Angelica gigas Nakai (AGN) is an oriental traditional medicine to treat anemia, dysmenorrhea, and migraine. However, its anti-lymphoma effect is yet to be tested. Here, we demonstrated that AGN and its major component decursin target Myc to suppress lymphomagenesis in vitro and in vivo. AGN inhibite...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Eungyoung, Nam, Jehyun, Chang, Woochul, Zulfugarov, Ismayil S., Okhlopkova, Zhanna M., Olennikov, Daniil, Chirikova, Nadezhda K., Kim, Sang-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043616/
https://ncbi.nlm.nih.gov/pubmed/30002430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28619-z
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