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Iron chelation increases the tolerance of Escherichia coli to hyper-replication stress

In Escherichia coli, an increase in the frequency of chromosome replication is lethal. In order to identify compounds that affect chromosome replication, we screened for molecules capable of restoring the viability of hyper-replicating cells. We made use of two E. coli strains that over-initiate DNA...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Charbon, Godefroid, Klitgaard, Rasmus N., Liboriussen, Charlotte Dahlmann, Thulstrup, Peter Waaben, Maffioli, Sonia Ilaria, Donadio, Stefano, Løbner-Olesen, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043582/
https://ncbi.nlm.nih.gov/pubmed/30002429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28841-9
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