CB(1) receptor activation induces intracellular Ca(2+) mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes

Accumulating evidence supports the role of astrocytes in endocannabinoid mediated modulation of neural activity. It has been reported that some astrocytes express the cannabinoid type 1 receptor (CB(1)-R), the activation of which is leading to Ca(2+) mobilization from internal stores and a consecuti...

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Published in:Sci Rep
Main Authors: Hegyi, Zoltán, Oláh, Tamás, Kőszeghy, Áron, Piscitelli, Fabiana, Holló, Krisztina, Pál, Balázs, Csernoch, László, Di Marzo, Vincenzo, Antal, Miklós
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043539/
https://ncbi.nlm.nih.gov/pubmed/30002493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-28763-6
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