Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum

IMPORTANCE: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by loss of upper and lower motor neurons. Although novel ALS genetic variants have been identified, the shared genetic risk between ALS and other neurodegenerative disorders remains poorly under...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Karch, Celeste M., Wen, Natalie, Fan, Chun C., Yokoyama, Jennifer S., Kouri, Naomi, Ross, Owen A., Höglinger, Gunter, Müller, Ulrich, Ferrari, Raffaele, Hardy, John, Schellenberg, Gerard D., Sleiman, Patrick M., Momeni, Parastoo, Hess, Christopher P., Miller, Bruce L., Sharma, Manu, Van Deerlin, Vivianna, Smeland, Olav B., Andreassen, Ole A., Dale, Anders M., Desikan, Rahul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6043387/
https://ncbi.nlm.nih.gov/pubmed/29630712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.0372
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