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Randomization Strategies Affect Motif Significance Analysis in TF-miRNA-Gene Regulatory Networks

Gene-regulatory networks are an abstract way of capturing the regulatory connectivity between transcription factors, microRNAs, and target genes in biological cells. Here, we address the problem of identifying enriched co-regulatory three-node motifs that are found significantly more often in real n...

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Dettagli Bibliografici
Pubblicato in:J Integr Bioinform
Autori principali: Sadegh, Sepideh, Nazarieh, Maryam, Spaniol, Christian, Helms, Volkhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: De Gruyter 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042831/
https://ncbi.nlm.nih.gov/pubmed/28675749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jib-2017-0017
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