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DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed. Because arenavirus nucleoprotein (NP) plays criti...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Loureiro, María Eugenia, Zorzetto-Fernandes, Andre Luiz, Radoshitzky, Sheli, Chi, Xiaoli, Dallari, Simone, Marooki, Nuha, Lèger, Psylvia, Foscaldi, Sabrina, Harjono, Vince, Sharma, Sonia, Zid, Brian M., López, Nora, de la Torre, Juan Carlos, Bavari, Sina, Zúñiga, Elina
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042795/
https://ncbi.nlm.nih.gov/pubmed/30001425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007125
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