DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection

Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-priority emerging diseases for which countermeasures are urgently needed. Because arenavirus nucleoprotein (NP) plays criti...

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發表在:PLoS Pathog
Main Authors: Loureiro, María Eugenia, Zorzetto-Fernandes, Andre Luiz, Radoshitzky, Sheli, Chi, Xiaoli, Dallari, Simone, Marooki, Nuha, Lèger, Psylvia, Foscaldi, Sabrina, Harjono, Vince, Sharma, Sonia, Zid, Brian M., López, Nora, de la Torre, Juan Carlos, Bavari, Sina, Zúñiga, Elina
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042795/
https://ncbi.nlm.nih.gov/pubmed/30001425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007125
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