FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis

Focal adhesion kinase (FAK) is an intensely studied non-receptor tyrosine kinase with roles in cancer and other common human diseases. Despite the large interest in FAK, the in vivo contribution of FAK auto-phosphorylation site tyrosine (Y) 397 to FAK function is incompletely understood. To study FA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Heim, Joel B., McDonald, Cera A., Wyles, Saranya P., Sominidi-Damodaran, Sindhuja, Squirewell, Edwin J., Li, Ming, Motsonelidze, Catherine, Böttcher, Ralph T., van Deursen, Jan, Meves, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042779/
https://ncbi.nlm.nih.gov/pubmed/30001432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200558
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