POFA trial study protocol: a multicentre, double-blind, randomised, controlled clinical trial comparing opioid-free versus opioid anaesthesia on postoperative opioid-related adverse events after major or intermediate non-cardiac surgery

INTRODUCTION: Reducing opioid consumption during and after surgery has been recommended for more than 10 years. Opioid-free anaesthesia (OFA) is a multimodal anaesthesia associating hypnotics, NMDA antagonists, local anaesthetics, anti-inflammatory drugs and α-2 agonists. Proofs of the effect of OFA...

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Bibliographic Details
Published in:BMJ Open
Main Authors: Beloeil, Helene, Laviolle, Bruno, Menard, Cedric, Paugam-Burtz, Catherine, Garot, Matthias, Asehnoune, Karim, Minville, Vincent, Cuvillon, Philippe, Oger, Sebastien, Nadaud, Julien, Lecoeur, Sylvain, Chanques, Gerald, Futier, Emmanuel
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2018
Subjects:
Anaesthesia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042576/
https://ncbi.nlm.nih.gov/pubmed/29961015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2017-020873
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