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Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation

BACKGROUND: The fully developed adult skeleton adapts to mechanical forces by generating more bone, usually at the periosteal surface. Progenitor cells in the periosteum are believed to differentiate into bone-forming osteoblasts that contribute to load-induced adult bone formation, but in vivo evid...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Moore, Emily R., Zhu, Ya Xing, Ryu, Han Seul, Jacobs, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042447/
https://ncbi.nlm.nih.gov/pubmed/29996901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0930-1
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