Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

BACKGROUND: Epilepsy is a prevalent neurological disorder worldwide. It is characterized by an enduring predisposition to generate seizures and its development is accompanied by alterations in many cellular processes. Organotypic slice cultures represent a multicellular environment with the potentia...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Magalhães, Daniela M., Pereira, Noémia, Rombo, Diogo M., Beltrão-Cavacas, Cláudia, Sebastião, Ana M., Valente, Cláudia A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6042335/
https://ncbi.nlm.nih.gov/pubmed/29996878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1225-2
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