Longevity of duodenal and peripheral T-cell and humoral responses to live-attenuated Salmonella Typhi strain Ty21a

BACKGROUND: We have previously demonstrated that polyfunctional Ty21a-responsive CD4(+) and CD8(+) T cells are generated at the duodenal mucosa 18 days following vaccination with live-attenuated S. Typhi (Ty21a). The longevity of cellular responses has been assessed in peripheral blood, but persiste...

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Publicado en:Vaccine
Main Authors: Pennington, Shaun H., Ferreira, Daniela M., Reiné, Jesús, Nyirenda, Tonney S., Thompson, Ameeka L., Hancock, Carole A., Wright, Angela D., Gordon, Stephen B., Gordon, Melita A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Science 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041722/
https://ncbi.nlm.nih.gov/pubmed/29958737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.05.114
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