A research pathway for the study of the delivery and disposition of nebulised antibiotics: an incremental approach from in vitro to large animal models

BACKGROUND: Nebulised antibiotics are frequently used for the prevention or treatment of ventilator-associated pneumonia. Many factors may influence pulmonary drug concentrations with inaccurate dosing schedules potentially leading to therapeutic failure and/or the emergence of antibiotic resistance...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Dhanani, Jayesh A., Cohen, Jeremy, Parker, Suzanne L., Chan, Hak-Kim, Tang, Patricia, Ahern, Benjamin J., Khan, Adeel, Bhatt, Manoj, Goodman, Steven, Diab, Sara, Chaudhary, Jivesh, Lipman, Jeffrey, Wallis, Steven C., Barnett, Adrian, Chew, Michelle, Fraser, John F., Roberts, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041222/
https://ncbi.nlm.nih.gov/pubmed/29998357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-018-0180-7
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