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Genome-wide association study identifies a regulatory variant of RGMA associated with opioid dependence in European Americans

BACKGROUND: Opioid dependence (OD) is at epidemic levels in the United States. Genetic studies can provide insight into its biology. METHODS: We completed an OD genome-wide association study (GWAS) in 3058 opioid-exposed European-Americans, 1290 of whom met criteria for a DSM-IV diagnosis of OD. Ana...

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Detaylı Bibliyografya
Yayımlandı:Biol Psychiatry
Asıl Yazarlar: Cheng, Zhongshan, Zhou, Hang, Sherva, Richard, Farrer, Lindsay, Kranzler, Henry R., Gelernter, Joel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041180/
https://ncbi.nlm.nih.gov/pubmed/29478698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.12.016
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