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Fork Protection and Therapy Resistance in Hereditary Breast Cancer

The BRCA-Fanconi anemia (FA) pathway preserves the genome and suppresses cancer and is a main determinant of chemotherapeutic efficacy. The hereditary breast cancer genes BRCA1 and BRCA2 function in DNA double-strand break repair mediating distinct steps of homologous recombination (HR). More recent...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cold Spring Harb Symp Quant Biol
Main Authors: Cantor, Sharon B., Calvo, Jennifer A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041132/
https://ncbi.nlm.nih.gov/pubmed/29472318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2017.82.034413
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