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Tannerella forsythia produced methylglyoxal causes advanced glycation endproducts (AGEs) accumulation to trigger cytokine secretion in human monocytes

The periodontal pathogen Tannerella forsythia has the unique ability to produce methylglyoxal (MGO) an electrophilic compound, which can covalently modify amino acid side chains and generate inflammatory adducts known as advanced glycation endproducts (AGEs). In periodontitis, the concentrations of...

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Detalhes bibliográficos
Publicado no:Mol Oral Microbiol
Main Authors: Settem, Rajendra P., Honma, Kiyonobu, Shankar, Mira, Li, Miaomiao, LaMonte, Michael, Xu, Ding, Genco, Robert J., Browne, Richard W., Sharma, Ashu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6041129/
https://ncbi.nlm.nih.gov/pubmed/29573211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12224
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