Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

BACKGROUND: An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the optimal treatment for these children. METHODS AND FINDINGS: To inform the pediatric aspects of the revised W...

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Udgivet i:PLoS Med
Main Authors: Harausz, Elizabeth P., Garcia-Prats, Anthony J., Law, Stephanie, Schaaf, H. Simon, Kredo, Tamara, Seddon, James A., Menzies, Dick, Turkova, Anna, Achar, Jay, Amanullah, Farhana, Barry, Pennan, Becerra, Mercedes, Chan, Edward D., Chan, Pei Chun, Ioana Chiotan, Domnica, Crossa, Aldo, Drobac, Peter C., Fairlie, Lee, Falzon, Dennis, Flood, Jennifer, Gegia, Medea, Hicks, Robert M., Isaakidis, Petros, Kadri, SM, Kampmann, Beate, Madhi, Shabir A., Marais, Else, Mariandyshev, Andrei, Méndez-Echevarría, Ana, Moore, Brittany Kathryn, Nargiza, Parpieva, Ozere, Iveta, Padayatchi, Nesri, ur-Rehman, Saleem-, Rybak, Natasha, Santiago-Garcia, Begoña, Shah, N. Sarita, Sharma, Sangeeta, Shim, Tae Sun, Skrahina, Alena, Soriano-Arandes, Antoni, van den Boom, Martin, van der Werf, Marieke J., van der Werf, Tjip S., Williams, Bhanu, Yablokova, Elena, Yim, Jae-Joon, Furin, Jennifer, Hesseling, Anneke C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040687/
https://ncbi.nlm.nih.gov/pubmed/29995958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002591
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