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CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1
Growing evidence demonstrates that the highly conserved serine/threonine kinase CK2 promotes Th17 cell differentiation while suppressing the generation of Foxp3(+) Tregs; however, the exact mechanism by which CK2 regulates the Th17/Treg axis remains unclear. CK2 can be comprised of 3 distinct subuni...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6040220/ https://ncbi.nlm.nih.gov/pubmed/29891553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701592 |
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