The effect of CYP2C9*2, CYP2C9*3, and VKORC1-1639 G>A polymorphism in patients under warfarin therapy in city of Kermanshah

Polymorphism in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence warfarin dose requirement since patients with CYP2C9*2, CYP2C9*3 and VKORC1 mutant alleles require lower warfarin maintenance doses. Studies have reported the ethnic variations in the frequency of these gen...

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Udgivet i:Res Pharm Sci
Main Authors: Hosseinkhani, Zohreh, Sadeghalvad, Mona, Norooznezhad, Fathemeh, Khodarahmi, Reza, Fazilati, Mohammad, Mahnam, Azadeh, Fattahi, Ali, Mansouri, Kamran
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6040167/
https://ncbi.nlm.nih.gov/pubmed/30065771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.235165
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