Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations

BACKGROUND & AIMS: The diarrheagenic pathogen, enteropathogenic Escherichia coli (EPEC), uses a type III secretion system to deliver effector molecules into intestinal epithelial cells (IECs). While exploring the basis for the lateral membrane separation of EPEC-infected IECs, we observed infect...

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Detalles Bibliográficos
Publicado en:Cell Mol Gastroenterol Hepatol
Main Authors: Roxas, Jennifer Lising, Monasky, Ross Calvin, Roxas, Bryan Angelo P., Agellon, Al B., Mansoor, Asad, Kaper, James B., Vedantam, Gayatri, Viswanathan, V.K.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039986/
https://ncbi.nlm.nih.gov/pubmed/30003123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2018.04.007
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