Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages

Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos. This high frequency of cellular extinction events represents a sign...

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Publicado en:Heliyon
Autores principales: Glinsky, Gennadi, Durruthy-Durruthy, Jens, Wossidlo, Mark, Grow, Edward J., Weirather, Jason L., Au, Kin Fai, Wysocka, Joanna, Sebastiano, Vittorio
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039856/
https://ncbi.nlm.nih.gov/pubmed/30003161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e00667
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