Evolution of a chemosensitive core-binding factor AML into an aggressive leukemia with eosinophilic differentiation

Core-binding factor AML can evolve from good-risk disease into aggressive disease through the gain of additional genomic aberrations. In this unique case, an AML patient died of hypereosinophilic syndrome with solid organ infiltration of differentiated eosinophils.

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Xiao, Wenbin, Yabe, Mariko, Offin, Michael, Khattar, Pallavi, Baik, Jeeyeon, Daley, Ryan J., Pappacena, Jeremy J., Roshal, Mikhail, Zhang, Yanming, Tallman, Martin S., Cai, Sheng F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Exceptional Case Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039660/
https://ncbi.nlm.nih.gov/pubmed/29950292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018016675
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