Antibody targeting of a specific region of Pfs47 blocks Plasmodium falciparum malaria transmission

Transmission-blocking vaccines are based on eliciting antibody responses in the vertebrate host that disrupt parasite development in the mosquito vector and prevent malaria transmission. The surface protein Pfs47 is present in Plasmodium falciparum gametocytes and female gametes. The potential of Pf...

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Détails bibliographiques
Publié dans:NPJ Vaccines
Auteurs principaux: Canepa, Gaspar E., Molina-Cruz, Alvaro, Yenkoidiok-Douti, Lampouguin, Calvo, Eric, Williams, Adeline E., Burkhardt, Martin, Peng, Fangni, Narum, David, Boulanger, Martin J., Valenzuela, Jesus G., Barillas-Mury, Carolina
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039440/
https://ncbi.nlm.nih.gov/pubmed/30002917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0065-5
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