Monotypic low-level HIV viremias during antiretroviral therapy are associated with disproportionate production of X4 virions and systemic immune activation

OBJECTIVE: During effective antiretroviral therapy (ART), low-level plasma viremias (LLV) (HIV RNA >30–1000 copies/ml) can be detected intermittently. We hypothesized that systemic inflammation is associated with LLV either as the cause or result of the production of virions from clonally expande...

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Bibliographische Detailangaben
Veröffentlicht in:AIDS
Hauptverfasser: Bull, Marta E., Mitchell, Caroline, Soria, Jaime, Styrchak, Sheila, Williams-Wietzikoski, Corey, Legard, Jillian, McKernan-Mullin, Jennifer, Kraft, Kelli, Onchiri, Frankline, Stern, Joshua, Holte, Sarah, Ryan, Kevin J., Acosta, Edward P., La Rosa, Alberto, Coombs, Robert W., Ticona, Eduardo, Frenkel, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2018
Schlagworte:
Basic Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039404/
https://ncbi.nlm.nih.gov/pubmed/29683841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001824
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