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The transcription factor SKN-1 and detoxification gene ugt-22 alter albendazole efficacy in Caenorhabditis elegans

Parasitic nematodes infect over 1/4 th of the human population and are a major burden on livestock and crop production. Benzimidazole class anthelmintics are widely used to treat infections, but resistance is a widespread problem. Mutation of genes encoding the benzimidazole target β-tubulin is a we...

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書目詳細資料
發表在:Int J Parasitol Drugs Drug Resist
Main Authors: Fontaine, Pauline, Choe, Keith
格式: Artigo
語言:Inglês
出版: Elsevier 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039320/
https://ncbi.nlm.nih.gov/pubmed/29793058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.04.006
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