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Bind3P: Optimization of a Water Model Based on Host-Guest Binding Data

We report a water model, Bind3P (Version 0.1), which was obtained by using sensitivity analysis to readjust the Lennard-Jones parameters of the TIP3P model against experimental binding free energies for six host-guest systems, along with pure liquid properties. Tests of Bind3P against >100 experi...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Yin, Jian, Henriksen, Niel M., Muddana, Hari S., Gilson, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039243/
https://ncbi.nlm.nih.gov/pubmed/29874074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.8b00318
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