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TSLP signaling in CD4(+) T cells programs a pathogenic T helper 2 cell state
Pathogenic T helper 2 (T(H)2) cells, which produce increased amounts of the cytokines interleukin-5 (IL-5) and IL-13, promote allergic disorders, including asthma. Thymic stromal lymphopoietin (TSLP), a cytokine secreted by epithelial and innate immune cells, stimulates such pathogenic T(H)2 cell re...
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| Gepubliceerd in: | Sci Signal |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6039124/ https://ncbi.nlm.nih.gov/pubmed/29535264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aam8858 |
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