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Statistical Issues and Limitations in Personalized Medicine Research with Clinical Trials
We discuss using clinical trial data to construct and evaluate rules that use baseline covariates to assign different treatments to different patients. Given such a candidate personalization rule, we first note that its performance can often be evaluated without actually applying the rule to subject...
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| Publicat a: | Int J Biostat |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6038934/ https://ncbi.nlm.nih.gov/pubmed/22850073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/1557-4679.1423 |
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