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Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2

OBJECTIVE: Beclin1 was previously found to be downregulated in human laryngeal cancer (LC) tissues, and it results in poor prognosis. This study aimed to further confirm the antitumor effects of Beclin1 in LC cell line Hep-2. MATERIALS AND METHODS: Beclin 1 was overexpressed in Hep-2 cells using lip...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Wan, Baoluo, Zang, Yanzi, Wang, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038865/
https://ncbi.nlm.nih.gov/pubmed/30013363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S148869
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