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Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2

OBJECTIVE: Beclin1 was previously found to be downregulated in human laryngeal cancer (LC) tissues, and it results in poor prognosis. This study aimed to further confirm the antitumor effects of Beclin1 in LC cell line Hep-2. MATERIALS AND METHODS: Beclin 1 was overexpressed in Hep-2 cells using lip...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wan, Baoluo, Zang, Yanzi, Wang, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038865/
https://ncbi.nlm.nih.gov/pubmed/30013363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S148869
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