AEG-1 is involved in hypoxia-induced autophagy and decreases chemosensitivity in T-cell lymphoma

BACKGROUND: This study was to examine the link between astrocyte elevated gene-1 (AEG-1) and hypoxia induced-chemoresistance in T-cell non-Hodgkin’s lymphoma (T-NHL), as well as the underlying molecular mechanisms. METHODS: Expression of AEG-1, LC3-II, and Beclin-1 were initially examined in human T...

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Pubblicato in:Mol Med
Autori principali: Yan, Jiaqin, Zhang, Junhui, Zhang, Xudong, Li, Xin, Li, Ling, Li, Zhaoming, Chen, Renyin, Zhang, Lei, Wu, Jingjing, Wang, Xinhua, Sun, Zhenchang, Fu, Xiaorui, Chang, Yu, Nan, Feifei, Yu, Hui, Wu, Xiaolong, Feng, Xiaoyan, Li, Wencai, Zhang, Mingzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038315/
https://ncbi.nlm.nih.gov/pubmed/30134829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0033-6
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