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Novel long-range regulatory mechanisms controlling PKD2 gene expression

BACKGROUND: Cis-regulatory elements control gene expression over large distances through the formation of chromatin loops, which allow contact between enhancers and gene promoters. Alterations in cis-acting regulatory systems could be linked to human genetic diseases. Here, we analyse the spatial or...

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Publicat a:BMC Genomics
Autors principals: Moisan, Stéphanie, Levon, Stéphanie, Cornec-Le Gall, Emilie, Le Meur, Yannick, Audrézet, Marie-Pierre, Dostie, Josée, Férec, Claude
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038307/
https://ncbi.nlm.nih.gov/pubmed/29986647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4892-6
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