miR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin gene

BACKGROUND: Metastasis is the leading cause of cancer mortality and is a major hurdle for lung cancer treatment. Invadopodia, which are cancer-specific protrusive structures, play a crucial role in the metastatic cascade through degradation of the basement membrane and surrounding stroma. Cortactin,...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Li, Yongwen, Zhang, Hongbing, Gong, Hao, Yuan, Yin, Li, Ying, Wang, Cong, Li, Weiting, Zhang, Zihe, Liu, Minghui, Liu, Hongyu, Chen, Jun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038252/
https://ncbi.nlm.nih.gov/pubmed/29986736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0824-1
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