A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis is a fatal lung disease characterized by a progressive formation of fibroblastic foci in the interstitium. This disease is strongly associated with telomere dysfunction but the extent of telomere shortening and consequent chromosomal damage within IPF lungs...

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Udgivet i:Respir Res
Main Authors: McDonough, John E., Martens, Dries S., Tanabe, Naoya, Ahangari, Farida, Verleden, Stijn E., Maes, Karen, Verleden, Geert M., Kaminski, Naftali, Hogg, James C., Nawrot, Tim S., Wuyts, Wim A., Vanaudenaerde, Bart M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038197/
https://ncbi.nlm.nih.gov/pubmed/29986708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0838-4
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