ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice

OBJECTIVES: The present study aimed to investigate cardiovascular autonomic modulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene. METHODS: Diabetic and non-diabetic mice harboring 2 o...

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Bibliografiske detaljer
Udgivet i:Clinics (Sao Paulo)
Main Authors: de Moraes, Oscar Albuquerque, Flues, Karin, Scapini, Kátia Bilhar, Mostarda, Cristiano, Evangelista, Fabiana de Sant’Anna, Rodrigues, Bruno, Dartora, Daniela Ravizzoni, Fiorino, Patricia, Angelis, Kátia De, Irigoyen, Maria Cláudia
Format: Artigo
Sprog:Inglês
Udgivet: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038058/
https://ncbi.nlm.nih.gov/pubmed/30088535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2018/e246
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