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Placental inflammation in pre‐eclampsia by Nod‐like receptor protein (NLRP)3 inflammasome activation in trophoblasts
Pre‐eclampsia is associated with increased levels of cholesterol and uric acid and an inflamed placenta expressing danger‐sensing pattern recognition receptors (PRRs). Crystalline cholesterol and uric acid activate the PRR Nod‐like receptor protein (NLRP)3 inflammasome to release interleukin (IL)‐1β...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6038006/ https://ncbi.nlm.nih.gov/pubmed/29683202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13130 |
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