Urocortin-2 Prevents Dysregulation of Ca(2+) Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion

Aims: Urocortin-2 (Ucn-2) is a potent cardioprotector against Ischemia and Reperfusion (I/R) injuries. However, little is known about its role in the regulation of intracellular Ca(2+) concentration ([Ca(2+)](i)) under I/R. Here, we examined whether the addition of Ucn-2 in reperfusion promotes card...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Domínguez-Rodríguez, Alejandro, Mayoral-Gonzalez, Isabel, Avila-Medina, Javier, de Rojas-de Pedro, Eva S., Calderón-Sánchez, Eva, Díaz, Ignacio, Hmadcha, Abdelkrim, Castellano, Antonio, Rosado, Juan A., Benitah, Jean-Pierre, Gomez, Ana M., Ordoñez, Antonio, Smani, Tarik
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037857/
https://ncbi.nlm.nih.gov/pubmed/30018568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00813
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