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Cisplatin-activated PAI-1 secretion in the cancer-associated fibroblasts with paracrine effects promoting esophageal squamous cell carcinoma progression and causing chemoresistance
Preoperative chemotherapy is a promising strategy for the treatment of esophageal squamous cell carcinoma (ESCC). Acquired resistance to chemotherapy is a major obstacle in improving patient prognosis. Cancer-associated fibroblasts (CAFs) are the primary components of the tumor microenvironment and...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Cell Death Dis |
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Κύριοι συγγραφείς: | , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group UK
2018
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6037765/ https://ncbi.nlm.nih.gov/pubmed/29988148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0808-2 |
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