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PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations

Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels during pre- and postnatal development. Macrocystic, microcystic and combined forms of LM are known. The cysts are lined by lymphatic endothelial cells (LECs). Resection and sclerotherapy are the most common treatme...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blesinger, Hannah, Kaulfuß, Silke, Aung, Thiha, Schwoch, Sonja, Prantl, Lukas, Rößler, Jochen, Wilting, Jörg, Becker, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037383/
https://ncbi.nlm.nih.gov/pubmed/29985963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200343
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