CTEN induces epithelial-mesenchymal transition (EMT) and metastasis in non small cell lung cancer cells

To explore the effects and mechanism of CTEN (COOH-terminus tensin-like molecule) on EMT, cell migration and invasion of Human lung adenocarcinoma cells. The pCMV-vector, pCMV-CTEN, Control-shRNA, and CTEN-shRNA were transfected into A549 and NCI-H1299 cells by Lipofectamine 2000. Transforming growt...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lu, Xiangdong, Gao, Juan, Zhang, Yao, Zhao, Tao, Cai, Hongchuan, Zhang, Tingrong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037349/
https://ncbi.nlm.nih.gov/pubmed/29985912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198823
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